Hamilton 1-0 St Johnstone: Accies sink nine-man Saints

first_imgThere was no sign of the controversy to come as the game got off to a quiet start.In the fourth minute Saints keeper Alan Mannus, who had replaced Zander Clark, parried a powerful drive from Accies midfielder Greg Docherty.Both sides soon became mired in pinball football, with possession surrendered as quickly as it was gained.Hamilton midfielder Ali Crawford and striker Rakish Bingham drove over the bar from outside the box as the Lanarkshire men took a measure of control, but the clear-cut chance they pursued remained absent. A last-gasp goal from Alex D’Acol gave Hamilton a 1-0 win over nine-man St Johnstone after Saints had two players sent off for brawling with each other at the SuperSeal stadium.When referee Don Robertson’s whistle sounded to end a nondescript first half, there were gasps of disbelief as Saints midfielder Danny Swanson and defender Richard Foster grappled.Players, management, and officials all got involved and the scenes of chaos ended with both players red carded inside at the interval.The Perth side were two men short for the second half but it looked like they would hold out for the point until D’Acol fired in a 90th-minute winner to take the home side off the bottom of the Ladbrokes Premiership table, two points above Inverness. A minute from the interval the ball fell kindly to Bingham following a corner but he slashed his shot from 12 yards high over the bar to the groans of the home fans.But that all paled into insignificance when the half-time whistle sounded and Foster and Swanson set about each other, with punches and kicks thrown and an ensuing rammy which saw Crawford booked and Accies assistant Guillaume Beuzelin sent from the technical area.Both Saints players were told to stay inside by Robertson and the visitors started the second half two men short, with 19-year-old defender Clive Smith replacing Blair Alston to make his debut following his loan move from Preston.As expected, the home side took control and Bingham missed the ball in front of goal as Accies pressed.Mannus saved a long-distance effort from captain Michael Devlin, who had been involved in a verbal spat with Accies winger Dougie Imrie at the start of the second half.St Johnstone were looking to hold out for the draw and it became a game of attack versus defence.Tommy Wright’s men were getting their heads to the numerous crosses which were thrown into their box, and as the second half progressed the attempts on goal deteriorated as the anxiety increased.Crawford did draw a good save from Mannus with a blistering drive in the 85th minute and it looked like the Perth side would leave with a point.However, Accies eventually got the breakthrough when D’Acol, inside the packed St Johnstone box, rifled in for a morale-boosting win, although the fall-out will focus on the startling altercation between Swanson and Foster.last_img read more

Daytime wounds heal more quickly than those suffered at night

first_imgDaytime wounds heal more quickly than those suffered at night Given the fibroblasts’ time-keeping abilities, O’Neill and colleagues searched for proteins within the cells that ebb and flow with daily rhythms. They came back with an unexpected result: Proteins that direct the construction of the cell’s actin-based skeleton worked daytime shifts. These cellular contractors tell fibroblasts to move into an injury to begin the healing process. So the finding suggests that the time of day a wound occurs may affect how quickly it heals. Such a “skyscraper” hypothesis seems reasonable, says Steven Brown, a chronobiologist at the University of Zurich in Switzerland who was not involved in the study. “To build a complex tissue over several days, it makes sense to import building materials in a regularly timed fashion,” he says.The researchers then tested that hypothesis with cells grown in a flat layer in a petri dish. The fibroblasts filled in scratches more quickly during the day than at night. “You can see by eye, when the cell is wounded only 8 hours apart from each other, in a different circadian phase, the [daytime] wounded ones take off, and the [nighttime] one drags,” O’Neill says.The researchers then showed in mice that skin wounds suffered during waking hours healed better than ones incurred during resting hours. What’s more, those increases lined up with the cell culture data. About twice as many fibroblasts migrated into the daytime wounds as nighttime ones. “We were really astonished,” O’Neill says.Finally, O’Neill and colleagues looked for evidence of such an effect in humans. The team examined data from the International Burn Injury Database, which records, among other things, the time of day an injury occurred. The analysis revealed that nighttime burns took an average of 11 days longer to heal than burns incurred during the day, the researchers report today in Science Translational Medicine. Brown calls the findings insightful. “I find it fascinating that even though wound healing takes days, a circadian clock is still used to optimize different aspects of the process.” O’Neill says that the time-varying response may be an evolutionary adaptation. As people are more likely to sustain injuries when awake than when sleeping, perhaps our bodies are primed to respond more quickly in the daytime. But he emphasizes the need for further controlled clinical studies to confirm the effect. He speculates that, if real, the effect could help people recover more quickly by scheduling surgeries in time with their personal circadian rhythms, earlier for morning larks and later for night owls.*Update, 13 November, 3:17 p.m.: This story has been updated to include comments from an outside researcher. The antidote to a bad scrape-up is usually a fairly simple recipe: antibiotics, bandages, and time. Now, a new study suggests that timing also matters. Skin cells that help patch up wounds work more quickly in the daytime than they do at night, thanks to the workings of our circadian clock. The finding suggests patients might recover from injury more quickly if they have surgery during the right time of day.Biologists and neuroscientists long thought the body’s time keeper, our circadian clock, resided only in the brain. In mammals, that place is a region of the hypothalamus called the suprachiasmatic nucleus, which receives signals from the eyes. However, recent research demonstrated that cells in other parts of the body—including the lungs and liver—keep their own time. Researchers aren’t quite sure how they maintain their own 24-hour schedule, whereas other cells need external reminders.To find out, John O’Neill, a biologist at the Medical Research Council’s Laboratory of Molecular Biology in Cambridge, U.K., and his team studied skin cells known as fibroblasts, which are essential for wound healing. Fibroblasts invade the void left by a scratch and lay the foundation for new skin to grow. The cells are also known to keep their own time. For example, cultured cells exhibit rhythmic oscillations in gene expression where there is no input from the master clock. Sign up for our daily newsletter Get more great content like this delivered right to you! Country Click to view the privacy policy. 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